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NaB-enhanced hepatic GLP-1R expression via inhibiting HDAC It has been reported that short-chain fatty acids (SCFAs) including NaB are able to regulate the immune response and metabolism through the activation of GPRs, such as GRP43 and GRP109a or through the inhibition of HDAC 27,28
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As a mitochondrial-derived peptide that activates the AMPK pathway, MOTS-C addresses the cellular energy dysfunction that underlies menopausal insulin resistance
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