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Interestingly, we found high hepatic expression of PGC-1 in mice that received high fat diet independent of drug treatment, whereas APAP per se halved the mRNA levels of PGC-1 in a chow diet background, thus implying a kind of protective mechanism exerted in normal conditions
Its a synthetic peptide derived from a protein found in human gastric juices
Biochem Pharmacol 34:11851189
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