Some of our patients have been on these medications for 20 plus years, and as long as they don't have any medical contraindications to the medication, they're doing fairly well on them." Bernotas says success depends on more than just taking the Wegovy pill
List cellular mechanisms: inflammation modulation, fibroblast ECM output, oxidative stress reduction, and glycation changes
Recently, administration of a long-acting GIP receptor agonist in humans, reduced GLP-1 analogue related gastrointestinal side effects, including nausea and vomiting (106)
Adherence Among 72,733 GLP-receptor agonist users who were alive 1 year after the date of filling their first prescription, 68% had 80% of proportion of days covered, 60% had 90% proportion of days covered, and 22% had 100% proportion of days covered