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We detected ACTL6A protein expression of 48 GC samples, those higher than the upper quartile are defined as high ACTL6A group, and those lower than the lower quartile are defined as low ACTL6A group

Damaged AECs release pro-inflammatory and pro-fibrotic mediators, including interleukin (IL) -1 and tumor necrosis factor (TNF) -, which promote fibroblast recruitment, inflammatory cell activation (e.g., neutrophils, Th17, gdT cells), and myofibroblast differentiation, ultimately leading to ECM accumulation and fibrotic tissue remodeling [20, 29, 33, 34]

LurzEHorneRGMaattanenPWuRYBottsSRLiBet alVitamin B12 deficiency alters the gut microbiota in a murine model of colitis

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