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GLP-1 medicines induce diuresis and natriuresis and reduce BP as well as albuminuria, an established marker of kidney dysfunction (30, 31)

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A preclinical study using Ts65Dn DS model mice ( n = 6) and wild-type littermates ( n = 6) found that high-fat diet increased beta-diversity and altered community composition, including a decrease in Eubacterium eligens , with beta-diversity effects greater in the DS model than in wild-type [187]

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