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A phase 2 randomised controlled trial published in the New England Journal of Medicine (2023) reported substantial weight loss and improvements in glycaemic parameters, though the trial was conducted in a closely monitored clinical setting with defined eligibility criteria

With antibiotics yet to be invented, scientists in the 1890s pioneered the field of immunotherapy by injecting bacteria into horses and then extracting the antibody-rich serum to use as treatment for humans

S-adenosylmethionine synthesis can be considered the rate-limiting step of the methionine cycle