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The consequences of dosing errors range from mild to serious

Health Considerations: Transdermal estrogen (patch, spray, or gel) is often preferred if you have certain risk factors, such as: High blood pressure Sedentary lifestyle Type-2 diabetes or high risk for it Family history of heart attack, stroke, or blood clotting disorders Age over 70, starting MHT after age 60, or more than 10 years after your last period Transdermal options bypass the liver and do not increase clotting factors, so they are associated with a lower risk of blood clots compared to oral estrogen

It can reduce the need for BP medications in some patients, but the goal is weight management with BP improvement as a downstream benefit, not BP control as the primary use

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