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41 In a randomized controlled trial in 162 couples with male infertility undergoing in vitro fertilization, those given 15 mg folic acid per day for three months had better outcomes than those given placebo: 44.1% of couples receiving folic acid were able to conceive and 35.6% had a viable pregnancy detectable on ultrasound at seven weeks of gestation compared with 22.4% and 20.4%, respectively, in those receiving placebo

Positive effects observed in studies include: Reduced liver fat accumulation Lower ALT and AST levels in patients with fatty liver Improved insulin sensitivity, which reduces liver workload Decreased inflammation markers Research published in The Lancet found that semaglutide significantly reduced liver fat and improved fibrosis markers in patients with metabolic dysfunction-associated steatohepatitis (MASH)

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