By competitively binding FOXO4, it prevents FOXO4 from sequestering p53, thereby restoring the cells intrinsic apoptotic signaling capacity
They are not illegal to buy or own - and widely available online - but they are not approved for human use, so are not subject to the quality controls that govern pharmaceutical manufacturing
Sustainable fat loss is about balance and consistency in exercise, eating habits, sleep, stress, and hormones (all of which, yes, evolve during midlife)
Yu DX, Di Giorgio FP, Yao J, Marchetto MC, Brennand K, Wright R, et al