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At postoperative day 21, defecation through vagina in controls ( c ) and a normal defecation in BPC 157 rats ( b ) ( Basically, closure of fistulas may be a measure of particular agents capacity to cure, at the same time, the skin wound and other corresponding tissues wound (Klicek et al., 2008

Payload conjugation was achieved through reduced interchain cysteines using either conventional maleimide chemistry or a more plasma-stable arylpropiolonitrile (APN) handle, resulting in well-defined ADCs with moderate drug loading