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Many patients experience a decrease in appetite and initial weight loss within the first 1 to 2 weeks
The STEP 1 trial (published in the New England Journal of Medicine) documented mean weight reductions of 14.9% with once-weekly semaglutide 2.4 mg compared to 2.4% with placebo, with corresponding improvements in waist circumference of approximately 13.5 cm with semaglutide versus 4.1 cm with placebo after 68 weeks
Bolignano D, Zoccali C
DOI: 10.3390/ijms23063266 [Google Scholar] Wijesinghe SN, Badoume A, Nanus DE, Sharma-Oates A, Farah H, Certo M, et al
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