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In addition, HU also acts as NO donor, promoting vasodilation (Nevitt et al., 2017)
Reported side effects include: Severe digestive problems, which may lead to acute kidney injury Gallbladder problems Pancreatitis Risk of thyroid cancer Severe allergic reaction In people with pre-existing kidney conditions, symptoms such as diarrhoea, nausea, and vomiting may lead to dehydration, potentially worsening kidney function
Only by addressing all of them together can we truly solve the healthcare cost crisis
Temporary dose reduction often allows symptom resolution while maintaining therapeutic benefit
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