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Their results show that the availability of extracellular GSH can alter sensitivity to different treatments, or even confer resistance to drugs that block the uptake of these amino acids, with the implications that entails
& Tao, Y
The SELECT trial established cardiovascular risk reduction in overweight adults without diabetes, while the STEP HFpEF program showed symptomatic improvement in heart failure with preserved ejection fraction [2]
In addition, the protective effects of both a recombinant adiponectin injection in ob/ob mice and metformin administration against NAFLD have been attributed, at least in part, to the inhibition of hepatic TNF expression 24,25
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