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J Biol Chem 286(33):2887628888 Kinlough CL, Poland PA, Bruns JB, Hughey RP (2005) Gamma-glutamyltranspeptidase: disulfide bridges, propeptide cleavage, and activation in the endoplasmic reticulum

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These effects have been attributed to improvements in insulin sensitivity, modulation of lipid metabolism, and activation of enteroendocrine and thermogenic gene programs

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The influence on the BPC-157 dopamine system, in particular, may explain some of the behavioral effects observed in animal studies, including antidepressant-like and anxiolytic-like activities

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