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Namely, the displacement of type A cells from the SVZ of the lateral ventricles to the olfactory bulb occurs through a tunnel-like structure composed of vascular cells and an astrocyte network driving the rostral flow of neuroblasts: the rostral migratory stream (Nguyen-Ba-Charvet et al., 2004)

And the clinical results have improved with each step up in receptor complexity

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One of the most effective treatments for obesity is bariatric surgery, which can lead to more weight loss and can even improve conditions like type 2 diabetes better than other methods