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In clinical trials, patients lost an average of 1517% of their body weight after 68 weeks when combined with diet and exercise

the majority maintaining levels under 7%

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The FDA titration schedule translated to units The FDA-recommended semaglutide titration schedule for weight management (based on the Wegovy approval) is: Weeks 1-4: 0.25 mg once weekly Weeks 5-8: 0.5 mg once weekly Weeks 9-12: 1 mg once weekly Weeks 13-16: 1.7 mg once weekly Week 17 onward: 2.4 mg once weekly (maintenance) This schedule applies to compounded semaglutide