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Neither is automatically the right answer, and the better choice depends on your chin, your budget and how you weigh evidence against cost

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Grant BJ, Rodrigues APC, ElSawy KM et al (2006) Bio3d: an R package for the comparative analysis of protein structures

2.2 AMPK signaling pathway AMPK is one of the central regulators of metabolism in eukaryotic cells and organisms, which can sense the intracellular energy status and maintain the stable operation of cellular physiological activities by sensing changes in intracellular AMP/ATP levels (Hardie et al., 2012)

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