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Chen, D., Liang, H., Huang, L., Zhou, H
For many, these signs might lead them to their GP, seeking answers and perhaps, a solution like a vitamin B12 injection
That pathway just took a meaningful step forward
As evidenced in db/db and ob/ob mouse models (Thaiss et al., 2018), sustained hyperglycemia activates intestinal epithelial glucose transporter 2 (GLUT2) and downregulates the expression of zonula occludens-1 (ZO-1), increasing intestinal permeability
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