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As part of a comprehensive weight loss program, GLP1s can support sustainable, long-term results when combined with a balanced diet and exercise plan

*Based on manufacturer trials studying the highest doses of oral Wegovy in non-diabetics with obesity, or with overweight plus a weight-related medical condition, when paired with diet and exercise changes (vs ~2% with diet and exercise alone)

For detailed comparison, see our guide on Mounjaro weight loss results

As the response to l-valine was not blocked in our study with a Na + -free lumen (where the activity of NHE3 must be abolished), it contradicts the role of PAT1 in l-valine induced GLP-1 secretion