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This oxidative burden leads to loss of mitochondrial membrane potential (m), cytochrome c release, disruption of cardiolipin binding, and subsequent ATP depletion due to impaired oxidative phosphorylation (OXPHOS)

But the strength of the evidence varies enormously according to the molecule, the formulation and the route of administration

In research related to colitis and gut inflammation, KPV was able to significantly reduce the presence of inflammatory cytokines and improve tissue regeneration