glp-1 patent Landscape: Who Leads the Innovation Race Pharma or Food? How the Future of GLP-1

adults now classified as obese and more than 70% overweight

Findings included: Average body weight reduction: 18.3% Average leg volume reduction (perometry): 11.4% Pain reduction (VAS score): improved from 6.2/10 to 3.1/10 on average 12 of 18 patients (67%) reported subjective softening of previously firm, nodular tissue While case series aren't definitive evidence, the leg volume reduction of 11.4% is notable because lipedema fat typically shows minimal response to weight loss interventions

Circulating INSL-5 levels are estimated to be in the picomolar range (164, 172), which is several orders of magnitude lower than the EC 50 of INSL-5 on RXRP4 (166) and the supraphysiological concentrations used in the majority of insulin secretion experiments may have contributed to the conflicting results

GH and IGF-1 both play roles in tissue repair, collagen synthesis, and cellular regeneration