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Topical applications may show initial improvements in skin texture and hydration within 2-4 weeks, with more significant changes in collagen production and skin firmness becoming apparent after 8-12 weeks of consistent use

To investigate the neural mechanisms of Cagrilintide, next-generation sequencing (NGS) was performed on three key hypothalamic and brainstem regions: the area postrema/nucleus tractus solitarius (AP/NTS), lateral parabrachial nucleus (LPBN), and ventromedial hypothalamus (VMH)

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