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when he does drink, he consumes 1-2 alcoholic beverages In terms of lifestyle, JM reports that he could eat better and that he engages in limited physical activity (estimated at 30 minutes per week of light walking) Laboratory and vital findings : Weight : 232 pounds (body mass index [BMI] = 34 kg/m 2 ) Blood pressure : 128/84 mmHg (average of 3 seated blood pressure readings) Blood glucose : 116 mg/dL (fasting) Point-of-care A1C : 7.1% Serum creatinine : 1.5 mg/dL eGFR : 50 mL/min/1.73 m 2 Sodium : 139 mEq/L Potassium : 4.9 mEq/L UACR : 60 mg/g (microalbuminuria) Low-density lipoprotein cholesterol (LDL-C): 88 mg/dL High-density lipoprotein cholesterol (HDL-C): 40 mg/dL Triglycerides: 148 mg/dL Case discussion JM provided some important information that will be helpful when determining a treatment plan to minimize his cardiovascular risk

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Anticancer activity Effects on carcinogen metabolism Inhibition of metabolic activation of carcinogens Some chemical carcinogens do not become active carcinogens until they have been metabolized by Phase I biotransformation enzymes, such as those belonging to the cytochrome P450 (CYP) family