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rat or mouse, the disease subtype of Diabetes mellitus (DM), the number of animals in this study utilized as the control group and the experimental or the DCM group, the dose, route of administration and the number of consecutive days the STZ was injected, the blood sugar cutoff point which confirms that diabetes was induced, the gender, age and bodyweight of the rodent species, and the primary outcomes reported by each included study are described in this table (Table 4)

It could also reduce astrogliosis and microgliosis in the dentate gyrus region of the hippocampus, prevent the impairment of pro-opiomelanocortin and G-protein-coupled receptor 43 expression caused by T2D, and simultaneously increase the number of NeuN+ and GLP-1R neurons in the hippocampus [Reference de Paiva, da Silva, Mendona, de Souza and Peixoto53]

Qual a composio das cpsulas

BPRS, Brief Psychiatric Rating Scale