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Follow-up imaging showed a stable pancreas

HPLC alone usually does not confirm identity

Receptor activation Despite the existence of unique structural features among the ligand-binding pockets of GIPR, GLP-1R and GCGR, both tirzepatide and peptide 20 triggered receptor conformational changes similar to that induced by GLP-1 or GCG 4,27 and distinct from the inactive or apo GLP-1R and GCGR structures (Supplementary Fig

However, GLP-1 RAs are also associated with emerging cutaneous adverse drug reactions, including bullous, exanthematous and vasculitic manifestations, and other rare side effects