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However, up to 89% of participants taking efinopegdutide experienced gastrointestinal adverse events (mostly nausea, vomiting and diarrhoea) relative to 28% taking placebo and 60% taking liraglutide (86)
they represent a powerful new tool
The review process under Health Canadas standard pathway takes approximately twelve months, though priority review can reduce this to six to eight months for medications addressing significant unmet needs
However, the precise effect of GLP-1 on fracture risk has not been unambiguously defined
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