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Although these discomforts usually ease with the bodys adaptation, they are still an issue that needs to be considered

The cost of these medications [to insurers], often ranging from $950 to $1,400 per month, has proven unsustainable and contributes significantly to rising premiums for individuals, employers, and the Commonwealth, said Lora Pellegrini, president of the Massachusetts Association of Health Plans, which represents Point32Health and about a dozen other insurers

Ergotamine is made up of indole alkaloids that are derived from a tetracyclic ergoline ring system (59)

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