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Mechanism [edit] Glutathione synthase catalyzes the chemical reaction ATP + gamma-L-glutamyl-L-cysteine + glycine ADP + phosphate + glutathione The 3 substrates of this enzyme are ATP, gamma-L-glutamyl-L-cysteine, and glycine, whereas its 3 products are ADP, phosphate, and glutathione
Longitudinal studies show that a baseline CNFL threshold of 14.1 mm/mm 2 predicts DN onset within 6 years with 67% sensitivity and 71% specificity [46]
FEBS J 277:50865096 Mandal PK, Ersland L (2019) Editorial: Predictive imagable biomarkers for neurodegenerative and neurodevelopmental diseases
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