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In the in vivo studies, co-administration of a binary RGDS nanogel with luciferase-expressing cells via a subcutaneous route showed an around 3.2-fold increase in bioluminescent signal which confirmed the proliferative or anti-apoptotic property of the RGDS nanogel
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This is a deep dive into the clinical data mechanism of action, efficacy numbers, safety profile, the Phase 3 program, and where it stands against the competition
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doi:10.1073/pnas.96.11.6161 46
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