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Mitochondrial permeability transition pore in Alzheimers disease: cyclophilin D and amyloid beta
The biomarker was meaningfully higher in GO (+ 147%), GO + amlodipine (+ 56%), GO + aminoguanidine (+ 95%), and GO + NAC (+ 136%) than BSA (Fig
It is commonly accompanied by hyperlipidemia which results from a disbalance between the rates of fatty acids synthesis and degradation and is characterized by elevated total cholesterol and low-density lipoprotein-cholesterol (LDL-C), thus providing the substrate for ROS-mediated lipid peroxidation (6366)
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