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Published rodent studies demonstrate that BPC-157 administered via intranasal route reaches systemic circulation and produces measurable effects on brain dopamine and serotonin metabolism supporting its use in CNS-focused research protocols where systemic injection may confound results

Gipr AP-KO mice had no alterations in circulating GIP, GLP-1 or insulin (Extended Data Fig

Furthermore, markedly elevated activities of APX, catalase and GST in a cytokinin-overproducing tobacco line were accompanied with a significantly lower number of HR-lesions and reduced levels of TNV, as compared to wild type controls (Pogny et al., 2004)