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GSH is primarily synthesized intracellularly through two consecutive reactions catalyzed by -glutamylcysteine synthetase (Gsh1 in eukaryotes and GshA in prokaryotes, encoded by GSH1 and gshA , respectively) and glutathione synthetase (Gsh2 in eukaryotes and GshB in prokaryotes, encoded by GSH2 and gshB , respectively)
Ben Rouina, S
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1998;160(2):389 to 393
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