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Whilst a single instance of minor dose reduction is unlikely to significantly impact glycaemic control, consistent under-dosing over multiple injections could potentially reduce the medication's effectiveness
doi:10.1042/0264-6021:3600001
semaglutide has more extensive cardiovascular outcome data Cardiovascular Disease: Semaglutide has proven heart benefits in SELECT trial Kidney Disease: Dosing adjustments may be needed for both Gastrointestinal Issues: Pre-existing GI problems may influence tolerance Lifestyle Factors: Neither medication works without lifestyle changes
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