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Studies show that NNMT inhibition by 5-amino-1-methylquinolinium significantly reduces nicotinamide metabolism, increases NAM accumulation, improves NAD+ synthesis efficiency by over 30%, and markedly increases mitochondrial ATP production and cellular energy metabolism
By inhibiting NNMT, 5-Amino-1MQ effectively disrupts this process, leading to a reduction in fat storage and promoting increased fat oxidation
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