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There is little difference in the histopathologic features of the original biopsy and the recurrent lesion

Its molecular mass is 873 Daltons, making it a small, stable compound that researchers have studied extensively since the early 1980s

Diabetes 41 , 490501 (2023)

We hypothesised that the reported brainstem transcriptomic changes might reflect modulation of NTS Ppg neuron activity downstream of GIPR antagonism in the hypothalamus and therefore tested the effect of GIPR-antag on mice with ablated NTS Ppg neurons (Ppg NTS-Abl ) generated by bilateral stereotactic injection of AAV-DTA into the NTS of Ppg-Cre or control mice (Cre-negative mice receiving AAV-DTA into the NTS) (Fig