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A Phase 1 Randomized, Double Blind, Placebo Controlled, Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CT-388 in Otherwise Healthy Overweight and Obese Adult Participants and in Obese Patients With Type 2 Diabetes Mellitus [Internet

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Strength work two to three times weekly helps maintain metabolic rate and functional capacity

For the acute cold tolerance test, food was removed at the time of transfer and body temperature was measured at the indicated time points