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Tirzepatide versus Semaglutide Once Weekly in Type 2 Diabetes (SURPASS-2) Fras JP, Davies MJ, Rosenstock J, et al
FIGURE 1 TABLE 1 Overview of all laboratory parameters following tirzepatide administration on day 0 (abnormal values are indicated in bold)
Furthermore, in another study [47, 60], one semaglutide analogue demonstrated a binding affinity to GLP-1R that is more than two orders of magnitude (113.3 times) higher than native semaglutide, achieving a K d of 3.0 10 8 M compared to the K d of 3.4 10 6 M for native semaglutide
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