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The primary end point (a composite of death from cardiovascular causes, non-fatal myocardial infarction, or non-fatal stroke) occurred in 305 patients with alogliptin (11.3%) and in 316 patients with placebo (11.8%), which was not significantly different
Dont assume the medication is going to eventually take care of it
Growth factor receptor-bound protein 2 (GRB2), an adaptor protein, binds to the receptor and recruits Son of Sevenless (SOS), a guanine nucleotide exchange factor (GEF)
However, the results may depend on genetic factors and more research is needed
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