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Interaction with H1/3 revealed 14 docking solutions at site 5, the DNA-binding domain, where the peptide bound with a minimum energy of 56.49 kcal/mol using the sequence His-Pro-Ser-Tyr-Met-Ala-His-Pro-Ala-Arg-Lys

These GLP-1 receptor agonists work by mimicking the hormone glucagon-like peptide-1 to regulate appetite, digestion, and blood sugar, but may cause side effects like nausea, diarrhea, or constipation, which are typically mild and improve over time