obesity drug news today glp-1 2025 🚨 Breaking in Care! 🚨 President Trump just announced major deals with Eli Lilly and Novo Nordisk — the makers of Mounjaro, Zepbound, Wegovy, and Ozempic — to slash weight New Guidelines on GLP-1 Drugs

Journal of Bacteriology

Any unusual or persistent reaction should be evaluated by a healthcare professional immediately

Severe gastrointestinal diseases and renal impairment : If you have these conditions or severe kidney dysfunction, well explore other options as Semaglutide GLP-1 can worsen these conditions and cause kidney-related side effects

centrally-mediated loss of appetite & increased thermogenic activity GLP-1 receptors are found in regions of the hindbrain and hypothalamus that regulate feeding behavior Centrally mediated GLP-1 effects include: reduction of food intake - resulting in weight loss due to reduced caloric intake activation of sympathetic pathways in the dorsomedial hypothalamus (DMH) and ventromedial nucleus of the hypothalamus (VMH) that increase neuronally mediated thermogenic activity of brown adipose tissue (BAT) resulting in increased energy expenditure with associated weight loss (Contreras et al, 2017