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This usually happens when theres a bleed somewhere in your upper GI tract, a bowel obstruction or youre severely constipated

Keywords: tumor resistance, glutathione S -transferase pi, drug treatment Introduction In addition to combating a variety of noxious substances from the external environment, cell-detoxification mechanisms are capable of resisting the deleterious effects of certain endogenous substances (eg, ROS, a product generated from normal cellular metabolism), in order to maintain physiological homeostasis

You will notice them at the top with a black box around them

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