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The systematic review protocol was registered in the International Prospective Register of Systematic Reviews (PROSPERO), registration number: CRD42024554513 (Available from) ( 2.2 PICOs question The primary research question addressed in this review was: What is the effectiveness of sublingual/oral administration of Vitamin B12 alone or compared to other forms of administration (e.g., intramuscular injection)?
In every case we've tracked, this coincides with either (a) return to baseline-poor sleep habits, (b) increased stress/cortisol load, or (c) dietary regression
The organ that is most affected by B12 deficiency is the nervous system and brain
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