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Swiss rolls allowed us to maximize the amount of tissue analyzed

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A small observational study published in JCI Insight (2022) examined individuals with obesity receiving semaglutide who reported reductions in alcohol intake, though the relationship to weight loss requires further investigation in controlled trials

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Despite this outcome, PD-1-mediated T-cell dysfunction in individuals with obesity was found to significantly enhance tumor responsiveness to PD-1/PD-L1 inhibitors, as confirmed by preclinical and clinical data

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A practical approach using membrane-active peptides as models

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