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While more research is needed, the outlook is cautiously hopeful for the first time in many years

[2] [4] These medications work by mimicking the action of naturally occurring GLP-1, a hormone released from the gut after eating

Separated proteins were transferred onto Immobilon-P Transfer membranes (MilliporeSigma, IPVH00010), blocked for 1 h using 5% BSA in TBS0.5% Tween-20 and stained overnight with primary rabbit-anti-GCLC (Sigma-Aldrich, HPA036359) or affinity-purified rabbit-anti-GGT1 (GGT129, as previously described 63 ) 1:1,000 in BSA 2.5% overnight at 4 C

Optimising thyroid replacement and evidence-based lifestyle interventions should be explored as first-line approaches before considering GLP-1 medications