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This paper is based just on spontaneous reports, which are sent to regulatory authorities in the country of the person reporting a suspected ADR
The Pediatric Neurology Advisory Committee in 1996 and some textbooks and manuals strongly recommended carnitine supplementation (50100 mg/kg per day) during VPA therapy for children at risk for developing a carnitine deficiency, in VPA overdose and in VHT [33, 92, 93]
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