Tirzepatide's dual GIP/GLP-1 mechanism may also produce a different GI side-effect profile in individual patients
Signs of more severe dehydration include (9): Little to no urination, or very dark yellow or amber-colored urine Dry, shriveled-looking skin Dizziness or lightheadedness Irritability or confusion Rapid heartbeat Rapid breathing Sunken eyes Extreme tiredness or listlessness In severe cases, shock or loss of consciousness Spotting these signs early can help you take action before dehydration becomes a bigger issue, especially if youre managing side effects from GLP-1 medications
Exclusion criteria: Non-RCTs (cohort, casecontrol, cross-sectional studies, case reports)
Fusco J, Xiao X, Prasadan K, Sheng Q, Chen C, Ming YC, et al (2017a) GLP-1/Exendin-4 induces -cell proliferation via the epidermal growth factor receptor