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In the UK, berberine is available over-the-counter as a food supplement regulated by the Food Standards Agency (FSA), not as a licensed medicine approved by the Medicines and Healthcare products Regulatory Agency (MHRA)

69 Likely mechanisms for these benefits include ginkgos well-established ability to combat oxidative stress through stimulating antioxidant enzyme activity, reducing reactive free radicals, and decreasing lipid peroxidation, 70 as well as possibly preventing noise-induced damage to cochlear synapses