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For instance, administering IGF-1R mAbs in cancer trials was reported to result in increased adverse events in younger populations 34 , including insulin resistance, possibly due in part to disruption of the somatotropic axis and associated deleterious effects of excess GH 41,42
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The Tirzepatide groups consistently showed shorter mean follow-up periods (390.09395.18 days), which corresponds to its more recent market introduction compared to the other medications studied (Supplementary Table 1)
Crunkhorn, S
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