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Tirzepatide versus insulin glargine as second-line or third-line therapy in type 2 diabetes in the asia-pacific region: the SURPASS-AP-combo trial
The exact mechanism of the dysesthesia side effect is not known, but researchers hypothesize it may be due to the activation of the glucagon or GLP-1 receptors, as these receptors are expressed on central and peripheral nerves
Metabolite standards were obtained from Sigma-Aldrich (Spruce St., St Louis, MO, United States)
Freeman is Professor of Neurology at Harvard Medical School and a world-renowned authority on neuropathic pain, neuropathic pain clinical trial design, and peripheral nervous system disorders
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