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Metabolic liver health (MASLD) A phase 2a randomised trial in Nature Medicine examined retatrutide in adults with metabolic-dysfunction-associated steatotic liver disease

Common side effects of topiramate include: Burning, numbness, or tingling in your feet, hands, face, or mouth (paresthesia) Dry mouth or altered taste Constipation, nausea, or stomach pain Dizziness, drowsiness, or slowed reactions Nervousness Headache Shaking or muscle weakness Nosebleeds Involuntary eye movements Menstrual irregularities Avoid alcohol and other central nervous system (CNS) depressants, such as sedatives and certain pain medications, as they can increase these side effects

Of course, not everyone will experience the same effects

Late-night meals can raise overnight glucose for some people